Experimental and clinical double lung transplantation

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Experimental models of lung transplantation.

Lung transplantation is a life saving treatment for end stage pulmonary diseases. The development and refinement of this therapy required the utilization of various animal models, without which this procedure would not have become a clinical reality. Canine models were critical in the initial breakthroughs in surgical technique and immunosuppressive regimens, which directly led to the first suc...

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Airway fire during double-lung transplantation.

Airway fire is a well-documented event during airway surgery with devastating outcomes. Individuals involved in the care of these patients should be aware of this possible complication and precautions needed to prevent this complication.

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Overview of clinical lung transplantation.

Since the first successful lung transplant 30 years ago, lung transplantation has rapidly become an established standard of care to treat end-stage lung disease in selected patients. Advances in lung preservation, surgical technique, and immunosuppression regimens have resulted in the routine performance of lung transplantation around the world for an increasing number of patients, with wider i...

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Severe reperfusion lung injury after double lung transplantation

AIM To demonstrate the effects of combined inhaled nitric oxide and surfactant replacement as treatment for acute respiratory distress syndrome. This treatment has not previously been documented for reperfusion injury after double lung transplantation. METHOD A 24-year-old female with cystic fibrosis underwent double lung transplantation. During implantation of the second lung a marked increa...

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Clamshell or sternotomy for double lung or heart-lung transplantation?

OBJECTIVE To evaluate the influence of either incision on the lungs and chest wall. METHODS Ninety-two double lung (DLT) or heart-lung (HLT) transplantations were done since January 1990. There were 22 (24%) hospital deaths, leaving 70 patients with complete data for evaluation. We did 38 DLT and 32 HLT for end-stage chronic respiratory failure (n = 22) and primary (n = 34) or secondary (n = ...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 1988

ISSN: 0022-5223

DOI: 10.1016/s0022-5223(19)35388-7